Single-cell analysis of intra-host variation

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inferring the inter-host transmission of influenza A virus using patterns of intra-host genetic variation.

Influenza A viruses (IAVs) cause acute, highly transmissible infections in a wide range of animal species. Understanding how these viruses are transmitted within and between susceptible host populations is critical to the development of effective control strategies. While viral gene sequences have been used to make inferences about IAV transmission dynamics at the epidemiological scale, their u...

متن کامل

Tools for Single-Cell Kinetic Analysis of Virus-Host Interactions.

Measures of cellular gene expression or behavior, when performed on individual cells, inevitably reveal a diversity of behaviors and outcomes that can correlate with normal or diseased states. For virus infections, the potential diversity of outcomes are pushed to an extreme, where measures of infection reflect features of the specific infecting virus particle, the individual host cell, as well...

متن کامل

Variation in mistletoe seed deposition: effects of intra- and interspecific host characteristics

We investigated differences in host infection by a desert mistletoe, Phoradendron californicum, and examined one of the processes that contributes to these differences: variation in seed deposition among host individuals and species. In the Sonoran Desert, P. californicum parasitizes the sympatric leguminous trees Olneya tesota, Cercidium microphyllum, Prosopis elutina, Acacia constricta, and A...

متن کامل

Tree phyllosphere bacterial communities: exploring the magnitude of intra- and inter-individual variation among host species

BACKGROUND The diversity and composition of the microbial community of tree leaves (the phyllosphere) varies among trees and host species and along spatial, temporal, and environmental gradients. Phyllosphere community variation within the canopy of an individual tree exists but the importance of this variation relative to among-tree and among-species variation is poorly understood. Sampling te...

متن کامل

Single Cell Analysis

> Automatisation for high throughput image acquisition. > Systems Biology: cell cycle regulatory network of S. meliloti. Outlook > Monitoring the dynamics of proteins implicated in the control of the bacterial cell cycle in individual cells is possible in PDMS chips in face of typical length scales of only 0.5 to 3 microns. > High cell viability visible in the observed division time of about 20...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nature Reviews Genetics

سال: 2014

ISSN: 1471-0056,1471-0064

DOI: 10.1038/nrg3770